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2-phenylbenzofuran derivatives, method for preparing the same and use of the same for treating inflammatory disease

机译:2-苯基苯并呋喃衍生物,其制备方法及其在治疗炎性疾病中的用途

摘要

The present invention relates to a novel 2-phenylbenzofuran derivative or a pharmaceutically acceptable salt thereof, a production method for the same, and a pharmaceutical composition for preventing or treating an inflammatory disease comprising the same as an active ingredient, and the novel 2-phenylbenzofuran derivative or the pharmaceutically acceptable salt thereof according to the present invention is outstandingly effective in suppressing NO, IL-6, and TNF-alpha induced by macrophages, and therefore can advantageously be used in a pharmaceutical composition for preventing or treating an inflammatory disease.
机译:本发明涉及新型的2-苯基苯并呋喃衍生物或其药学上可接受的盐,其制备方法以及用于预防或治疗以其为有效成分的炎性疾病的药物组合物,以及新型的2-苯基苯并呋喃。根据本发明的衍生物或其药学上可接受的盐在抑制由巨噬细胞诱导的NO,IL-6和TNF-α方面非常有效,因此可以有利地用于预防或治疗炎性疾病的药物组合物中。

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