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PROCESS FOR PRODUCING ITACONIC ACID UNDER ANAEROBIC CONDITIONS
PROCESS FOR PRODUCING ITACONIC ACID UNDER ANAEROBIC CONDITIONS
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机译:厌氧条件下生产衣康酸的方法
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摘要
The present invention relates to a method for the production of itaconic acid, which method comprises fermenting a recombinant cell capable of producing itaconic acid in a suitable fermentation medium, thereby to produce itaconic acid, wherein: (a) the recombinant cell: (i) overexpresses cis-aconitate decarboxylase; and (ii) overexpresses a part of the citric acid cycle and/or has reduced activity of a native metabolic route to acetate and/or lactate; and, optionally, (b) the fermentation is carried out under anaerobic conditions.
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