Limited fossil sources and an increasing awareness of sustainability problems pave the way for integrated process concepts for the conversion of renewable raw materials. The efficient production of platform molecules represents the key for a sustainable and economic competitive process concept of future biorefineries. Itaconic acid was identified as a promising platform molecule from lignocellulosic biomass [1] for the production of fuels [2], polymers and a variety of additional products [3], but it has not yet reached industrial scale production. While the global production in 2009 was only 80 kt/a [4], the potential non-fuel market volume for 2020 is envisioned to be 200 to 6000 kt/a [5]. For the envisioned market volume and a successful replacement of petrochemicals in the named applications, the process efficiency in terms of economy, energy efficiency and productivity needs to be improved. These open tasks can only be successfully addressed by a systematic analysis of existing and development of alternative processing strategies. This work shows the improvement potential for the production of itaconic acid by analyzing and developing alternative fermentation and downstream processing concepts.
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机译：有限的化石来源以及增加对可持续性问题的认识，为可再生原材料转换的综合过程概念铺平了道路。平台分子的有效生产代表了可持续和经济竞争过程的未来生物杂交概念的关键。透康酸被鉴定为来自木质纤维素生物量[1]的有前景平台分子，用于生产燃料[2]，聚合物和各种额外的产品[3]，但尚未达到工业规模生产。虽然2009年的全球产量仅为80千克/ A [4]，但2020年的潜在非燃料市场体积被设想为200至6000千克/ A [5]。对于设想的市场体积和成功的替代石化在命名应用中，需要改善经济，能源效率和生产力方面的过程效率。这些开放任务只能通过对替代加工策略的现有和开发的系统分析来成功解决。通过分析和开发替代发酵和下游加工概念，这项工作表明了衣康酸生产的改善潜力。
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