A system and method providing cross-ontology multi-master replication is described. In a first embodiment a method for cross-ontology multi-master replication comprising the steps of: obtaining, at an importing site, an exporting site ontology and a set of one or more database changes; wherein the exporting site ontology defines a set of one or more data types; and after mapping the exporting site ontology to an importing site ontology, incorporating the set of one or more database changes into a database including mapping each of one or more data types of the set of data types to a data type defined by the importing site ontology using an ontology map.
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