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Inhibition of Cytokine-Induced SH2 Protein in NK Cells
Inhibition of Cytokine-Induced SH2 Protein in NK Cells
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机译:细胞因子诱导的SH2蛋白在NK细胞中的抑制作用
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摘要
The present invention relates to therapeutic and prophylactic methods based on inhibition of CIS in NK cells. In particular, the present invention relates to treating or preventing a NK-responsive condition by administering to a subject a CIS inhibitor, or administering CIS-inhibited NK cells. The invention further relates to methods for identifying a CIS inhibitor, and for determining a likelihood of cancer response to treatment with CIS inhibition.
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