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IMMUNOTHERAPY TARGETING OF THE SHARED ABNORMAL CONFORMATIONAL STATE OF AMYLOIDOGENIC PEPTIDES/PROTEINS

机译：淀粉样蛋白原/蛋白质的共享异常构象状态的免疫治疗靶向

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摘要

The present invention is directed to pharmaceutical agents and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.

机译：本发明涉及可用于治疗和预防受试者淀粉样疾病的药物和组合物。本发明进一步涉及分离的抗体，该抗体识别淀粉样蛋白生成的蛋白质或肽的常见构象表位，其可用于诊断，治疗和预防淀粉样蛋白疾病。

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公开/公告号US2018305407A1

专利类型
公开/公告日2018-10-25

原文格式PDF
申请/专利权人 NEW YORK UNIVERSITY;
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申请/专利号US201715830902
发明设计人 THOMAS M. WISNIEWSKI;FERNANDO GONI;
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申请日2017-12-04
分类号C07K7/08;A61K38/10;A61K39;C07K16/18;A61K9;A61K39/395;
国家 US
入库时间 2022-08-21 13:00:23

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