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Immunotherapy targeting of the shared abnormal conformational state of amyloidogenic peptides/proteins
Immunotherapy targeting of the shared abnormal conformational state of amyloidogenic peptides/proteins
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机译:针对淀粉样蛋白肽/蛋白质共有异常构象状态的免疫疗法
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摘要
The present invention is directed to pharmaceutical agents and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.
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