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HOMOLOGOUS RECOMBINATION IN MULTIPOTENT ADULT PROGENITOR CELLS
HOMOLOGOUS RECOMBINATION IN MULTIPOTENT ADULT PROGENITOR CELLS
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机译:多能成人祖细胞中的同源重组
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摘要
The invention relates to methods of altering gene expression by homologous recombination in a multipotent adult progenitor cell (MAPC). In particular, methods of producing a recombinant MAPC, of correcting a genetic defect in a mammal, of providing a functional and/or therapeutic protein to a mammal, and of transforming a MAPC are provided. MAPCs containing an erogenous DNA as well as recombinant MAPCs and their differentiated progeny are also provided.
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