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USE OF A PCV2 IMMUNOGENIC COMPOSITION FOR LESSENING CLINICAL SYMPTOMS IN PIGS

机译:使用PCV2免疫原性组合物减轻猪的临床症状

摘要

The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 2 (PCV2) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV2 infection. Preferably, they include lymphadenopathy, lymphoid depletion and/or multinucleated/giant histiocytes. Moreover, the clinical symptoms include lymphadenopathy in combination with one or a multiple of the following symptoms in pigs: (1) interstitial pneumonia with interlobular edema, (2) cutaneous pallor or icterus, (3) mottled atrophic livers, (4) gastric ulcers, (5) nephritis and (6) reproductive disorders, e.g. abortion, stillbirths, mummies, etc. Furthermore the clinical symptoms include Pia like lesions, normally known to be associated with Lawsonia intracellularis infections.
机译:本发明涉及包含2型猪圆环病毒(PCV2)抗原的免疫原性组合物用于治疗几种临床表现(疾病)的用途。优选地,临床表现与PCV2感染有关。优选地,它们包括淋巴结病,淋巴样消耗和/或多核/巨人组织细胞。此外,临床症状包括猪淋巴结病,并伴有以下一种或多种以下症状:(1)间质性肺炎伴小叶间水肿,(2)皮肤苍白或黄疸,(3)斑驳的萎缩性肝脏,(4)胃溃疡,(5)肾炎和(6)生殖疾病,例如流产,死产,木乃伊等。此外,临床症状包括Pia样病变,通常已知与胞内劳森菌感染有关。

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