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EML4-ALK FUSION GENE

机译:EML4-ALK融合基因

摘要

The present inventors found that a fusion gene present in some cancer patients is an oncogene. The present invention relates to a polypeptide as a novel fusion protein, a polynucleotide encoding the polypeptide, a vector comprising the polynucleotide, a transformed cell comprising the vector, a method for detecting the fusion protein or polynucleotide, a method for screening a therapeutic agent for cancer, and a method for treating cancer that is shown to be positive for the fusion gene. Further, the present invention relates kit, primer set, and probe useful in the detection of cancer that is shown to be positive for the fusion gene
机译:本发明人发现存在于某些癌症患者中的融合基因是癌基因。本发明涉及作为新型融合蛋白的多肽,编码该多肽的多核苷酸,包含该多核苷酸的载体,包含该载体的转化细胞,用于检测融合蛋白或多核苷酸的方法,用于筛选治疗剂的方法。癌症,以及对融合基因呈阳性的癌症治疗方法。此外,本发明涉及试剂盒,引物组和探针,可用于检测对融合基因呈阳性的癌症

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