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3D PRINTED TRANS-MODULAR SCAFFOLDS FOR GRAFTING APPLICATIONS IN SEGMENTAL BONE DEFECTS

机译:3D打印的跨模架在节段性骨缺损中的移植应用

摘要

A bone repair scaffold having two moduli that match those of the cancellous and cortical bone in a patient receiving a bone graft/implant. The bone repair scaffold possesses increased mechanical properties to sustain physiological loading and biologically active capability to facilitate bone fusion. The bone repair scaffold may be 3D-printed, which allows for a variety of scaffold designs and configurations. Pore size, interconnected porosity, shape, and modulus of the bone repair scaffold may be modified for different bone graft applications, whether it is used as filler for bone cancer resections or trauma, or as a fusion device in cases of surgery. Depending on the defect location of the bone shaft, the relative porosity of the scaffold may be modified to account for changes in cortical bone thickness. A method for treating a bone defect using the bone repair scaffold is also disclosed.
机译:一种具有两个模量的骨修复支架,该模量与接受骨移植物/植入物的患者的松质骨和皮质骨的模量相匹配。骨修复支架具有增强的机械性能以维持生理负荷和促进骨融合的生物活性能力。骨修复支架可以是3D打印的,其允许各种支架设计和构造。可以修改骨修复支架的孔径,相互连接的孔隙率,形状和模量,以适合不同的骨移植应用,无论是用作骨癌切除术或创伤的填充物,还是手术中的融合装置。取决于骨轴的缺陷位置,可以改变支架的相对孔隙率以解决皮质骨厚度的变化。还公开了一种使用骨修复支架治疗骨缺损的方法。

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