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COMPOSITION FOR THE PREVENTION, IMPROVEMENT, OR TREATMENT OF NEUROLOGICAL DISORDER INCLUDING ADIPONECTIN RECEPTOR-ACTIVATING NOVEL PEPTIDE AS ACTIVE INGREDIENT
COMPOSITION FOR THE PREVENTION, IMPROVEMENT, OR TREATMENT OF NEUROLOGICAL DISORDER INCLUDING ADIPONECTIN RECEPTOR-ACTIVATING NOVEL PEPTIDE AS ACTIVE INGREDIENT
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机译:预防,改善或治疗神经系统疾病的组合物,包括作为活性成分的脂联素受体激活型新肽
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摘要
A method for preventing, improving or treating a neurological disorder includes administering to a subject a composition including an adiponectin receptor-activating novel peptide as an active ingredient. The adiponectin receptor-activating novel peptide is a peptide consisting of 5 amino acids, and when the adiponectin receptor-activating novel peptide is administered to Alzheimer's model mice, the mice's behavioral changes show that memory and cognitive functions are significantly increased, and APP and amyloid beta (Aβ) proteins are significantly reduced, cytotoxicity does not occur, the proliferation rate of neurons is increased, and cell death is inhibited.
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