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Universal influenza vaccine based on heterologous multiple M2E proteins
Universal influenza vaccine based on heterologous multiple M2E proteins
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机译:基于异源多种M2E蛋白的通用流感疫苗
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摘要
Disclosed are universal influenza A vaccines capable of providing broader crossprotection. The vaccine contains a fusion protein comprising tandem repeats of heterologous M2e epitope sequences that have been molecularly and genetically designed to provide broad cross-protection. The fusion protein may be incorporated into virus-like particles (VLPs) or a replicating live attenuated influenza virus vaccine, and administered alone or in combination with other influenza vaccines.
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