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Formation of neuromuscular junctions in a co-culture comprising rat muscle cells overlayered with differentiated human spinal cord stem cells in a serum free medium
Formation of neuromuscular junctions in a co-culture comprising rat muscle cells overlayered with differentiated human spinal cord stem cells in a serum free medium
A method for forming neuromuscular junctions includes forming functional neuromuscular junctions between motoneurons and muscle cells by co-culturing one or more human motoneurons and one or more rat muscle cells in a substantially serum-free medium. A synthetic mammalian neuromuscular junction includes a human motoneuron functionally linked to a rat muscle cell in a substantially serum-free medium. An artificial substrate may be used to support the one or more neuromuscular junctions.
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