首页> 外国专利> SUBGROUP B RECOMBINANT HUMAN ADENOVIRUS VECTOR, AND METHODS FOR CONSTRUCTING AND FOR USING THE SAME

SUBGROUP B RECOMBINANT HUMAN ADENOVIRUS VECTOR, AND METHODS FOR CONSTRUCTING AND FOR USING THE SAME

机译：子群B重组人腺病毒载体，以及构建和使用该载体的方法

页面导航

摘要
著录项
相似文献

摘要

A subgroup B recombinant human adenovirus vector Ad11-5EP (SEQ ID NO: 1), which is constructed by a method including: substituting a 365 bp fragment containing an enhancer and a promoter of an upstream coding sequence of Ad5 E1A (SEQ ID NO: 2) for a corresponding region of a serotype Ad11 (SEQ ID NO: 3) of a subgroup B human adenovirus vector by homologous recombination to construct the subgroup B recombinant human adenovirus vector Ad11-5EP (SEQ ID NO: 1).

机译：B亚组重组人腺病毒载体Ad 11 - 5 EP（SEQ ID NO：1），其通过以下方法构建：取代含有增强子的365bp片段同源重组构建B亚型人腺病毒载体血清型Ad11（SEQ ID NO：3）相应区域的Ad5 E1A（SEQ ID NO：2）上游编码序列的启动子和启动子腺病毒载体Ad11-5EP（SEQ ID NO：1）。 展开▼

著录项

公开/公告号US2018187214A1

专利类型

公开/公告日2018-07-05

原文格式PDF

申请/专利权人 BEIJING BIO-TARGETING THERAPEUTICS TECHNOLOGY INC.;
展开▼

申请/专利号US201815904408

发明设计人 YAOHE WANG;GUOZHONG JIANG;HANSHI WONG;FENGYU CAO;NICK LEMOINE;
展开▼

申请日2018-02-25

分类号C12N15/86;A61K35/761;C12N7;

国家 US

入库时间 2022-08-21 12:57:26

相似文献

专利

外文文献

中文文献

1. 重组溶瘤腺病毒、用于制备该重组溶瘤腺病毒的重组溶瘤腺病毒载体及其构建方法和应用 [P] . 中国专利： CN108424932B . 2021.01.05

2. 重组溶瘤腺病毒、用于制备该重组溶瘤腺病毒的重组溶瘤腺病毒载体及其构建方法和应用 [P] . 中国专利： CN108424932A . 2018-08-21

3. Subgroup B recombinant human adenovirus vector, and methods for constructing and for using the same [P] . 美国专利： US10294493B2 . 2019-05-21

机译： B亚组重组人腺病毒载体及其构建和使用方法

4. Subgroup B recombinant human adenovirus vector, and methods for constructing and for using the same [P] . 美国专利： US9932606B2 . 2018-04-03

机译： B亚组重组人腺病毒载体及其构建和使用方法

5. SUBGROUP B RECOMBINANT HUMAN ADENOVIRUS VECTOR, AND METHODS FOR CONSTRUCTING AND FOR USING THE SAME [P] . 美国专利： US2016222413A1 . 2016-08-04

机译：子群B重组人腺病毒载体，以及构建和使用该载体的方法

1. Recombinant adenovirus vector-mediated human MDA-7 gene transfection suppresses hepatocellular carcinoma growth in a mouse xenograft model [J] . Xinting Pan, Liqun Wu, Jingyu Cao, 生物医学研究杂志（英文版） . 2012,第001期

2. Recombinant adenovirus vector-mediated human MDA-7 gene transfection suppresses hepatocellular carcinoma growth in a mouse xenograft model [J] . Xinting Pan, Liqun Wu, Jingyu Cao, 生物医学研究杂志：英文版 . 2012,第001期

3. Construction of a recombinant adenovirus Vector of human papillomavirus type 16 L1_E7c [J] . 中国癌症研究（英文版） . 2000,第001期

4. Construction and Characterization of a Novel Recombinant Attenuated and Replication-Deficient Candidate Human Adenovirus Type 3 Vaccine:‘‘Adenovirus Vaccine Within an Adenovirus Vector'''''''' [J] . Yuqian Yan, Shuping Jing, Liqiang Feng, 中国病毒学：英文版 . 2021,第003期

5. Recombinant adenovirus type 5 vectors that target DC-SIGN, ChemR23 and alpha(v)beta3 integrin efficiently transduce human dendritic cells and enhance presentation of vectored antigens [J] . Maguire CA, Sapinoro R, Girgis N, Vaccine . 2006,第5期

6. Introduction of human beta-defensin-3 into cultured human keratinocytes and fibroblasts by recombinant adenovirus vectors--are primary cells able to secrete sufficient amounts of transgene to exhibit biological activity in vitro? [J] . Jacobsen F, Rittig A, Steinstraesser L Burns: Including Thermal Injury . 2011,第7期

7. An Agglomerative Method to Construct Discrepant Cohesive Subgroups [C] . Hecking Tobias, Gohnert Tilman, Hoppe H. Ulrich 2012 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining. . 2012

8. Characterisation of DNA damage inducible responses and repair in human cells using recombinant adenovirus vectors. [D] . Francis, Murray Albert. 2000

9. Biodistribution and Toxicological Safety of Adenovirus Type 5 and Type 35 Vectored Vaccines Against Human Immunodeficiency Virus-1 (HIV-1) Ebola or Marburg Are Similar Despite Differing Adenovirus Serotype Vector Manufacturers Construct or Gene Inserts [O] . Rebecca L. Sheets, Judith Stein, Robert T. Bailer, -1

10. Comparative Seroprevalence and Immunogenicity of Six Rare Serotype Recombinant Adenovirus Vaccine Vectors from Subgroups B and D▿ [O] . Abbink, Peter, Lemckert, Angelique A. C., Ewald, Bonnie A., 2007

11. Targeted Tumor Therapy by Use of Recombinant Adenovirus Vectors That Selectively Replicate in Hypoxic Regions of Tumors. [R] . Li, C. Y., Huang, Q., Dewhirst, M. W. 2003

1. Construction and Expression of Human PTEN Tumor Suppressor Gene Recombinant Adenovirus Vector [J] . CHEN Qingyong ,WANG Chunyou ,CHEN Daoda . 华中科技大学学报（医学）（英德文版） . 2006,第003期

2. The construction and expression of human GM-CSF recombinant adenovirus vector [J] . Hirofumi Hamada . 中国实验血液学杂志 . 1997,第3期

3. 人QKI6基因重组腺病毒载体的构建及其在心肌细胞中的表达鉴定 [C] . HU Xing-lin ,胡杏林 ,ZHENG Qiang-sun . 全国第十三届心脏学会、第十六届心功能学会和《心脏杂志》编委会联合学术会议 . 2013

4. 人NT3、BDNF基因真核表达载体和四环素可诱导重组腺病毒载体的构建及鉴定 [A] . 李志全 . 2004