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Abiraterona acetate in the form of nanoemulsu00e3o and process of obtaining abiraterona acetate in the form of nanoemulsu00e3o

机译:纳米乳形式的醋酸阿比特龙酯和纳米乳形式的醋酸阿比特龙酯的制备方法

摘要

Summary abiraterona acetate in the form of nanoemulsu00e3o and process of obtaining abiraterona acetate in the form of nanoemulsu00e3o this invention belongs to the technology sector of medicine pFor the treatment of cancer and refers more specifically to new forms of oral administration of the anticancer agent abiraterona acetate.For this purpose, will be developed nanoemulsu00f5es for oral use, systems that allow a significant gain in bioavailability and improve the solubility of the abiraterona acetate.Furthermore, these formulations promote the release of the drug at the site of action.Allowing the quantity daily administered is significantly lower than the currently recommended in the package leaflet in commercial use.With that,The invention represents a significant alternative for the treatment of prostate cancer resistant to castration due to reduction of the cost of treatment from the use of a formulation withSmall amount of abiraterona acetate without loss in relation to its therapeutic action and safety.In this way, the access to the drug will be facilitated to individuals with lower income or places with fewer financial resources for public health.
机译:概述纳米乳剂形式的乙酸阿比特龙酯和获得纳米乳剂形式的乙酸阿比特龙酯的方法本发明属于药物p的技术领域,用于治疗癌症,更具体地涉及口服形式的抗癌剂为此,将开发用于口服的纳米乳剂,该系统可显着提高生物利用度并改善乙酸阿比特龙酯的溶解度。此外,这些制剂还可以促进药物在作用部位的释放允许的每日给药量显着低于商业用途包装说明书中当前推荐的量。因此,由于降低了使用后的治疗成本,本发明代表了一种治疗去势抵抗性前列腺癌的重要替代方案。少量乙酸阿比特龙酯的制剂的制备的治疗作用和安全性。通过这种方式,收入较低的个人或公共卫生财政资源较少的地方将可以方便地获得药物。

著录项

  • 公开/公告号BR102016015171A2

    专利类型

  • 公开/公告日2018-01-16

    原文格式PDF

  • 申请/专利权人 GILBERTO SCHWARTSMANN;

    申请/专利号BR20161015171

  • 发明设计人 GILBERTO SCHWARTSMANN;

    申请日2016-06-28

  • 分类号A61K9/107;A61K31/58;A61P35/00;

  • 国家 BR

  • 入库时间 2022-08-21 12:54:02

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