Method for imunodiagnóstico of acute and chronic toxoplasmosis

摘要

This patent application discloses recombinant antigens or synthetic T. gondii useful for diagnosing acute and chronic toxoplasmosis.Disclosed are combinations for detection of IgG antibodies to T. gondii IgM antibodies and anti T. gondii, which comprise antigens GRA7, rop1, p35 and GRA6, or fragments thereof.In addition, this patent application discloses nucleotide sequences that encode the antigens of the present invention.As well as systems for recombinant expression and purification systems of these antigens.In addition, they are also provided with the stabilized compositions comprising the antigens of the invention, as well as those antigens coupled to microspheres.