首页> 外国专利> Formulated the basis of copaiba biodisponibilizados for oral use and topic associated with therapeutic applications in analgesia, inflammation and scarring

Formulated the basis of copaiba biodisponibilizados for oral use and topic associated with therapeutic applications in analgesia, inflammation and scarring

机译:制定了用于口服的copaiba biodisponibilizados的基础,以及与止痛,炎症和疤痕形成治疗相关的主题

摘要

Samples of copaiba (OCP) species of Copaifera reticulata ducke and Copaifera multijuga Hayne, as well as a commercial sample of this oil have been conducted (0.5% - 1,0%) in the microemulsion or nanoemulsu00e3o with characteristics SMEDDS and snedds, respectively.Specifically, this study aimed to optimize the therapeutic action of OCP in oral administration and topical associated, applied in the process of skin tissue repair.With action herbal medicine analgesic, anti-inflammatory and wound healing.The bioformulados of OCP were assessed via experimental protocols in vivo in skin wound and by the method of analgesia via inhibition of abdominal contortions induced by acetic acid.Having presented the activities of anti-inflammatory analgesic, wound healing and satisfactory.The antiseptic effect, which inhibits the proliferation of microorganisms, as well as extensive applications in dermatology and musculoskeletal therapy.Are also being claimed for the bioformulados of OCP.In addition to the use of oral and topic associated with the slow release and controlled of OCP in cellular membranes, via transdermal administration, also is the target of the claim.
机译:在具有SMEDDS和snedds特性的微乳液或纳米乳中,进行了Copaifera reticulata ducke和Copaifera multijuga Hayne的copaiba(OCP)样品以及该油的商业样品(0.5%-1,0%),具体而言,本研究旨在优化OCP在口服和局部给药方面的治疗作用,并在皮肤组织修复过程中应用。以中草药止痛,抗炎和伤口愈合的作用为基础,评估了OCP的生物制剂。通过抑制乙酸引起的腹部扭曲而在皮肤伤口中进行的体内实验和通过镇痛的方法。具有抗炎止痛的活性,伤口愈合良好,具有杀菌作用,抑制了微生物的繁殖,如在皮肤病学和肌肉骨骼疗法中的广泛应用.OCP的生物制剂也被要求保护。经由透皮给药,在细胞膜中与OCP的缓慢释放和控制有关的口服和主题的使用也是权利要求的目标。

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