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CD20 and CD22 Therapies, Therapies Combination Therapies with a cell that expresses a Chimeric Antigen receptor (CAR) of CD19

机译:CD20和CD22疗法,联合疗法与表达CD19嵌合抗原受体(CAR)的细胞的疗法

摘要

The invention provides ingredients and methods for treating diseases related to CD19 expression, for example, managing a recombinant cell, including CD19 as described herein, plus one or more B-cell inhibitors, for example, one or more B-cell inhibitors. The invention of CD10, CD20, CD22, CD34, CD123, Flt-3, ror1, CD79b, cd179b or CD79a also provides new antigen binding domains and car molecules, which all point to CD20 and CD22 and their applications,For example, as a single therapy or combination therapy, the invention also provides the toolkit and components described in this document.
机译:本发明提供了用于治疗与CD19表达有关的疾病的成分和方法,例如,管理重组细胞,包括本文所述的CD19,以及一种或多种B细胞抑制剂,例如一种或多种B细胞抑制剂。 CD10,CD20,CD22,CD34,CD123,Flt-3,ror1,CD79b,cd179b或CD79a的发明还提供了新的抗原结合域和汽车分子,它们都指向CD20和CD22及其应用,例如对于单一疗法或组合疗法,本发明还提供了该文件中描述的工具箱和组件。

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