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New Derivatives of fosfinanos and azafosfinanos, its method of Preparation and Pharmaceutical compositions containing them

机译:福辛诺和氮杂福辛的新衍生物,其制备方法和含有它们的药物组合物

摘要

Formula compound (I) (see attached image), where AK1 represents an asphalt chain, X represents - (CH2) m -,-Ch (R)..-N (R) --CH2-N (R) -,N (R) -CH2- o -CH2-N (R) -CH2-M and R are defined in the description, R1 and R2 represent each h, when X represents - (CH2) m -.-Ch (R)..-N (R) --CH2-N (R) - o N (R) -CH2-Or, when X represents - ch2-n (R) - CH2, they form an alliance,R3 represents NH2, cy-nh2, cy-ak3-nh2 or piperidin-4-ilo, cy and ak3, as defined in the description, R4 and R5 are the same or different, respectively representing h or F, the salts of their optical isomers and their acceptable pharmaceutical additives. Drugs.
机译:式(I)的化合物(参见附图),其中AK1代表沥青链,X代表-(CH2)m-,-Ch(R)..- N(R)--CH2-N(R)-,N (R)-CH 2 -o-CH 2 -N(R)-CH 2 -M和R在说明书中定义,当X表示-(CH 2)m -.- Ch(R)时,R 1和R 2代表每个h。 -N(R)-CH2-N(R)-N(R)-CH2-或,当X代表-ch2-n(R)-CH2时,它们形成一个联盟,R3代表NH2,cy-nh2,如说明书中所定义的cy-ak3-nh2或哌啶子基4-ilo,cy和ak3,R4和R5相同或不同,分别代表h或F,它们的旋光异构体的盐和它们可接受的药物添加剂。毒品。

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