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Trifluoromethyl alcohol as roryt modulator (divisional 2017-0166)

机译:三氟甲醇作为罗瑞特调节剂(分部2017-0166)

摘要

1. The invention includes a compound of the first formula, in which the definitions of X, A1, A2, A3, A4, R1, R2 and R3 are contained in the specification. The invention also includes a method for treating or improving syndrome, disorder or disease, in which the syndrome, disorder or disease is rheumatoid arthritis or Soria disease. In addition, the invention also includes a method for regulating the activity of Rort in mammals by effective treatment of at least one compound according to the first requirement.
机译:本发明包括第一式的化合物,其中X,A1,A2,A3,A4,R1,R2和R3的定义包含在说明书中。本发明还包括用于治疗或改善综合征,病症或疾病的方法,其中所述综合征,病症或疾病是类风湿性关节炎或索里亚病。此外,本发明还包括通过有效治疗至少一种根据第一要求的化合物来调节哺乳动物中的罗特活性的方法。

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