首页> 外国专利> NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR APPLICATION IN IMMUNOTHERAPY AND METHODS OF OBTAINING FRAMEWORK FOR APPLICATION IN THE TREATMENT OF CANCER AND OTHER CANCER TYPES

NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR APPLICATION IN IMMUNOTHERAPY AND METHODS OF OBTAINING FRAMEWORK FOR APPLICATION IN THE TREATMENT OF CANCER AND OTHER CANCER TYPES

机译:用于免疫治疗的新肽和肽组合以及在癌症和其他类型的癌症治疗中应用的研究方法

摘要

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to cancer immunotherapy. The present invention further relates to tumor-associated peptide T-cell epitopes, alone or in combination with other tumor-associated peptides, which may, for example, serve as active pharmaceutical ingredients of vaccine compositions that stimulate antitumor immune responses, or stimulate T-cells ex vivo with their transfer to the patient. Peptides associated with molecules of the major histocompatibility complex (MHC), or peptides individually, can also be targets for antibodies, soluble T-cell receptors and other binding molecules.
机译:本发明涉及用于免疫治疗方法的肽,蛋白质,核酸和细胞。特别地,本发明涉及癌症免疫疗法。本发明进一步涉及单独或与其他肿瘤相关肽组合的肿瘤相关肽T细胞表位,其例如可以用作刺激抗肿瘤免疫应答或刺激T-抗原的疫苗组合物的活性药物成分。细胞离体转移到患者体内。与主要组织相容性复合物(MHC)的分子相关的肽或单独的肽也可以作为抗体,可溶性T细胞受体和其他结合分子的靶标。

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