NEW PEPTIDES, PEPTIDE COMBINATIONS AND FRAMEWORK FOR APPLICATION IN THE IMMUNOTHERAPEUTIC METHOD OF TREATING DIFFERENT CANCER TYPES

摘要

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to cancer immunotherapy. The present invention further relates to tumor-associated peptide T-cell epitopes, alone or in combination with other tumor-associated peptides, which may, for example, serve as active pharmaceutical ingredients of vaccine compositions that stimulate antitumor immune responses, or stimulate T-cells ex vivo with their transfer to the patient. Peptides associated with molecules of the major histocompatibility complex (MHC), or peptides individually, can also be targets for antibodies, soluble T-cell receptors and other binding molecules.