METHODS OF SEQUENCING, DETERMINING, PAIRING, AND VALIDATING THERAPEUTIC AGENTS AND DISEASE SPECIFIC ANTIGENS.

摘要

Provided herein are methods and composition for immune repertoire sequencing and single cell barcoding. The methods and compositions can be used to pair any two sequences originating from a single cell, such as heavy and light chain antibody sequences, for antibody discovery, disease and immune diagnostics, and low error sequencing.