首页> 外国专利> TREATMENT OF TUMOR SUPPRESSOR GENE RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO THE GENE.

TREATMENT OF TUMOR SUPPRESSOR GENE RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO THE GENE.

机译：通过抑制天然的抗转录基因来治疗与肿瘤抑制基因有关的疾病。

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摘要

The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Tumor Suppressor genes, in particular, by targeting natural antisense polynucleotides of Tumor Suppressor genes. The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of Tumor Suppressor genes.

机译：本发明涉及特别是通过靶向肿瘤抑制基因的天然反义多核苷酸来调节肿瘤抑制基因的表达和/或功能的反义寡核苷酸。本发明还涉及这些反义寡核苷酸的鉴定及其在治疗与肿瘤抑制基因表达相关的疾病和病症中的用途。

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公开/公告号MX358603B

专利类型
公开/公告日2018-08-28

原文格式PDF
申请/专利权人 CURNA INC.;
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申请/专利号MX20150009333
发明设计人 JOSEPH COLLARD;OLGA KHORKOVA SHERMAN;
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申请日2009-12-03
分类号C12N15/11;A61K31/712;A61P35;C07H19;C12N15/63;C12Q1/68;
国家 MX
入库时间 2022-08-21 12:50:56

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