Therapeutic agent for diseases based on the inhibitory effect of the macrophage migration inhibitory factor

摘要

A benzopyran derivative represented by general formula [1], or a salt thereof, is useful in therapeutic or preventive treatment of disease, wherein said therapeutic or preventive treatment is effective because said benzopyran derivative, or salt thereof, binds to MIF, has an MIF inhibitory effect, and inhibits MIF. [In the formula, R 1 represents an optionally substituted C 1-6 alkyl group, one of R 2 and R 3 represents a hydrogen atom, and the other of R 2 and R 3 represents a hydrogen atom, an optionally substituted amino group, an optionally substituted acylamino group, an optionally substituted carbamoyl group, or an optionally substituted aryl group.]