Implantable device to assess autonomic cardiovascular control in a patient suffering from chronic cardiac dysfunction

摘要

An implantable device (11) for evaluating autonomous cardiovascular control, comprising: an implantable neuro-stimulator (12) comprising a pulse generator configured to provide a therapeutic therapeutic stimulation adjusted to restore autonomous balance through electric cycle pulses continuous, intermittent and periodic supplied so that the creation and propagation (in both afferent and efferent directions) of action potentials within neuronal fibers comprising a cervical vagus nerve (15, 16, 61) of a patient (10) is caused in continuous alternating cycles of stimulus application and inhibition of stimuli (90) and configured to deliver therapeutic electrical stimulation according to stored stimulation parameters comprising a pulse width that is within the range of 100 to 250 μsec, an output current (96) which is within the range of 0.02 to 50 mA, and a signal frequency (93) which is at least 10 Hz to about 20 Hz; a cervical vagus nerve stimulation therapy cable (13) electrically coupled to the pulse generator and terminating at least one electrode through which therapeutic electrical stimulation is supplied to the patient's cervical vagus nerve (15, 16, 61) .