首页> 外国专利> IMPLANTABLE DEVICE FOR EVALUATING AUTONOMIC CARDIOVASCULAR DRIVE IN A PATIENT SUFFERING FROM CHRONIC CARDIAC DYSFUNCTION

IMPLANTABLE DEVICE FOR EVALUATING AUTONOMIC CARDIOVASCULAR DRIVE IN A PATIENT SUFFERING FROM CHRONIC CARDIAC DYSFUNCTION

机译:评估患有慢性心功能不全的患者中自主性心血管驱动的可移植设备

摘要

An implantable device (11) for evaluating autonomic cardiovascular drive, comprising:an implantable neurostimulator (12) comprising a pulse generator configured to deliver electrical therapeutic stimulation tuned to restore autonomic balance through continuously-cycling, intermittent and periodic electrical pulses delivered in a manner that results in creation and propagation (in both afferent and efferent directions) of action potentials within neuronal fibers comprising a cervical vagus nerve (15, 16, 61) of a patient (10) in continuous alternating cycles of stimuli application and stimuli inhibition (90) and configured to deliver the electrical therapeutic stimulation according to stored stimulation parameters comprising the pulse width falling within the range of 100 to 250 µsec, the output current (96) falling within the range of 0.02 to 50 mA, and the signal frequency (93) at least being 10 Hz;a cervical vagus nerve stimulation therapy lead (13) electrically coupled to the pulse generator and terminated by a at least one electrode through which the therapeutic electrical stimulation is delivered to the patient's cervical vagus nerve (15, 16, 61).
机译:一种用于评估自主性心血管驱动的可植入设备(11),包括:植入式神经刺激器(12),包括脉冲发生器,该脉冲发生器配置为传递电治疗刺激,该电刺激经调整以通过连续循环,间歇和周期性电脉冲传递的方式恢复自律平衡,该方式导致产生和传播(沿传入和传出方向)在刺激施加和刺激抑制(90)的连续交替循环中,构成患者(10)的子宫颈迷走神经(15、16、61)的神经元纤维内的动作电位,并配置为根据存储的刺激参数传递电治疗刺激,包括脉冲宽度为100〜250μsec的范围,输出电流(96)为0.02〜50mA的范围,信号频率(93)为10Hz以上。子宫颈迷走神经刺激治疗导线(13),其电耦合至脉冲发生器,并由至少一个电极终止,治疗性电刺激通过至少一个电极传递到患者的子宫颈迷走神经(15、16、61)。

著录项

  • 公开/公告号EP3388106A1

    专利类型

  • 公开/公告日2018-10-17

    原文格式PDF

  • 申请/专利权人 CYBERONICS INC.;

    申请/专利号EP20180156736

  • 申请日2012-12-06

  • 分类号A61N1/05;A61N1/36;A61B5;A61B5/024;

  • 国家 EP

  • 入库时间 2022-08-21 13:17:46

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