Alpha-derivatives of cis-monounsaturated fatty acids for use as medications in the treatment of diabetes

摘要

Compound selected from: α-hydroxy-cis-Δ9-hexadecenoic acid (OHHD), α-hydroxy-cis-Δ9-octadecenoic acid (OHOD), α-methyl-cis-Δ9-octadecenoic acid (MOD), α-amino acid -cis-Δ9-octadecenoic acid (AOD), α-fluoro-cis-Δ9-octadecenoic acid (FOD), α-trifluoromethyl-cis-Δ9-octadecenoic acid (TFMOD), α-methoxy-cis-Δ9-octadecenoic acid (MOOD ), α-mercapto-cis-Δ9-octadecenoic acid (SHOD), α-methyl-cis-Δ11-octadecenoic acid (MOD11), α-hydroxy-cis-Δ11-octadecenoic acid (OHOD11), α-hydroxy-cis acid -Δ11-eicosenoic acid (OHEE), α-hydroxy-cis-Δ13-docosenoic acid (OHDE), sodium salt of α-hydroxy-cis acid - Δ9-octadecenoic acid (Na-OHOD), α-hydroxy-cis-Δ9- methyl octadecenoate (OMe-OHOD), ethyl α-hydroxy-cis-Δ9-octadecenoate ethyl (EE-OHOD), ammonium salt of α-hydroxy-cis-Δ9-octadecenoic acid (NH3-OHOD), α-acetyl- cis-Δ9-octadecenoic acid (ACOD), sodium salt of α-acetyl-cis-Δ9-octadecenoic acid (Na-ACOD), α-acetyl-cis-Δ9-octadecenoate methyl (OMe-ACOD), ethyl α-acetyl-cis-Δ9-octadecenoate (EE-ACOD), sodium salt of α-methoxy-cis-Δ9-octadecenoic acid (Na-MOOD), α-methoxy-cis-Δ9 -methyl octadecenoate (OMe-MOOD), ethyl α-methoxy-cis-Δ9-octadecenoate (EE-MOOD), α-diethyl-phosphatidyl-cis-Δ9-octadecenoic acid (DEPOD), α-diethyl acid sodium salt -phosphatidyl-cis-Δ9-octadecenoic (Na-DEPOD), methyl α-diethyl-phosphatidyl-cis-Δ9-octadecenoate (OMe-DEPOD) or ethyl α-diethyl-phosphatidyl-cis-Δ9-octadecenoate (EE-DEPOD ), for use, independently or in combination with at least one other compound, as a medicament or nutraceutical, in the treatment of diabetes.