首页> 外国专利> METHOD FOR PRODUCING L-PHENYLEPHRINE USING AN ALCOHOL DEHYDROGENASE OF AROMATOLEUM AROMATICUM EBN1 (AZOARCUS SP. EBN1)

METHOD FOR PRODUCING L-PHENYLEPHRINE USING AN ALCOHOL DEHYDROGENASE OF AROMATOLEUM AROMATICUM EBN1 (AZOARCUS SP. EBN1)

机译：香精EBN1（AZOARCUS SP.EBN1）的醇脱氢酶生产L-苯丙氨酸的方法

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摘要

The present invention relates to a multi-stageprocess for producing substituted, optically active alcohols,comprising an enzyme-catalyzed synthesis step, inparticular a synthesis step which is catalyzed by an alcoholdehydrogenase. The inventive method is particularly suitablefor producing phenylephrine, i.e. 3-[(1R)-1-hydroxy-2-methylamino-ethyl]-phenol.

机译：本发明涉及多级生产取代的光学活性醇的方法，包括酶催化的合成步骤，特别是由醇催化的合成步骤脱氢酶。本发明的方法特别适合用于生产去氧肾上腺素，即3-[（1R）-1-羟基-2-甲基氨基乙基]-苯酚。

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公开/公告号CA2735769C

专利类型
公开/公告日2018-10-09

原文格式PDF
申请/专利权人 BASF SE;
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申请/专利号CA20092735769
发明设计人 SIEGEL WOLFGANG;BREUER MICHAEL;HAUER BERNHARD;PLETSCH ANDREAS;
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申请日2009-09-15
分类号C12P41/00;C12P13/00;
国家 CA
入库时间 2022-08-21 12:48:20

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1. L-氨基酸脱氨酶全细胞转化L-苯丙氨酸生产α-苯丙酮酸 [C] . 侯颖 ,刘龙 ,李江华 . 中国生物工程学会2014年学术年会暨全国生物技术大会 . 2014

2. 利用苯丙氨酸解氨酶转化反式肉桂酸生产L-苯丙氨酸的研究 [A] . 熊彬 . 2005