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SYSTEMS AND METHODS FOR TOMOGRAPHIC IMAGING IN DIFFUSE MEDIA USING A HYBRID INVERSION TECHNIQUE
SYSTEMS AND METHODS FOR TOMOGRAPHIC IMAGING IN DIFFUSE MEDIA USING A HYBRID INVERSION TECHNIQUE
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机译:使用混合反演技术在弥散介质中进行层析成像的系统和方法
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摘要
The invention relates to systems and methods for tomographic imaging in diffuse media employing a fast reconstruction technique. A hybrid Fourier approach is presented that enables the fast tomographic reconstruction of large datasets. In certain embodiments, the invention features methods of in vivo fluorescence molecular tomographic (FMT) reconstruction of signals, reporters and/or agents (i.e., contrast agents or probes) in a diffusive medium (e.g., a mammalian subject). The method preserves the three-dimensional fluorophore distribution and quantitative nature of the FMT approach while substantially accelerating its computation speed, allowing FMT imaging of larger anatomies.
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