Development of tomographic reconstruction for three-dimensional optical imaging:From the inversion of light propagation to artificial intelligence

摘要

Optical molecular tomography(OMT)is an imaging modality which uses an optical signal,especially near-infrared light,to reconstruct the three-dimensional information of the light source in biological tissue.With the advantages of being low-cost,noninvasive and having high sensitivity,OMT has been applied in preclinical and clinical research.However,due to its serious ill-posedness and illcondition,the solution of OMT requires heavy data analysis and the reconstruction quality is limited.Recently,the artificial intelligence(commonly known as AI)-based methods have been proposed to provide a different tool to solve the OMT problem.In this paper,we review the progress on OMT algorithms,from conventional methods to AI-based methods,and we also give a prospective towards future developments in this domain.