首页> 外国专利> METHODS FOR PROPHYLACTICALLY PREVENTING, SLOWING THE PROGRESSION OF, OR TREATING ALZHEIMER'S DISEASE

METHODS FOR PROPHYLACTICALLY PREVENTING, SLOWING THE PROGRESSION OF, OR TREATING ALZHEIMER'S DISEASE

机译:预防性地预防,减慢或治疗老年痴呆症的进展的方法

摘要

The present specification is directed to systems, apparatus and methods for prophylactically preventing, or for treating the progression of, Alzheimer's disease. The progression of, stabilizing, or improving Symptoms related to Alzheimer's Disease (AD) are treated by monitoring a pathophysiological change indicative of AD in a patient, based on the monitoring, determining if amyloid plaque is present in a perivascular space of the patient, optionally determining an extent of amyloid plaque in the perivascular space, and based on the presence of amyloid plaque in the perivascular space of the patient, determining a treatment protocol for the patient. The treatment protocol includes administering to the patient a high density lipoprotein composition derived from mixing a blood fraction with a lipid removing agent.
机译:本说明书针对用于预防性预防或治疗阿尔茨海默氏病的系统,设备和方法。与阿尔茨海默氏病(AD)相关的症状的进展,稳定或改善,可以通过监测患者体内指示AD的病理生理变化来进行治疗,从而确定患者的血管周空间中是否存在淀粉样蛋白斑确定血管周围空间中淀粉样斑块的程度,并基于患者血管周围空间中淀粉样斑块的存在,确定患者的治疗方案。该治疗方案包括向患者施用源自将血液级分与脂质去除剂混合的高密度脂蛋白组合物。

著录项

  • 公开/公告号CA3053491A1

    专利类型

  • 公开/公告日2018-09-07

    原文格式PDF

  • 申请/专利权人 HDL THERAPEUTICS INC.;

    申请/专利号CA20183053491

  • 发明设计人 BREWER HOLLIS BRYAN JR.;MATIN MICHAEL M.;

    申请日2018-03-01

  • 分类号A61K9/107;A61K31/575;A61K31/661;A61K38/17;A61P25/28;C07K14/775;G01N33/92;

  • 国家 CA

  • 入库时间 2022-08-21 12:47:25

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