首页> 外国专利> Methods for Prophylactically Preventing, Slowing the Progression of, or Treating Cerebral Amyloid Angiopathy, Alzheimer's Disease and/or Acute Stroke

Methods for Prophylactically Preventing, Slowing the Progression of, or Treating Cerebral Amyloid Angiopathy, Alzheimer's Disease and/or Acute Stroke

机译:预防性预防,减缓或治疗脑淀粉样血管病,阿尔茨海默氏病和/或急性中风的方法

摘要

The present specification is directed to systems, apparatus and methods for prophylactically preventing, or for treating the onset and/or progression of Cerebral Amyloid Angiopathy (CAA), acute stroke conditions, or Alzheimer's disease. The progression of, stabilizing, or improving symptoms related to these conditions are treated by monitoring a pathophysiological change indicative of the conditions in a patient, based on the monitoring, determining if amyloid plaque is present in a perivascular space of the patient, optionally determining an extent of amyloid plaque in the perivascular space, and based on the presence of amyloid plaque in the perivascular space of the patient, determining a treatment protocol for the patient. The treatment protocol includes administering to the patient a high density lipoprotein composition derived from mixing a blood fraction with a lipid removing agent.
机译:本说明书针对用于预防性预防或治疗脑淀粉样血管病(CAA),急性中风病或阿尔茨海默氏病的系统,设备和方法。与这些病症相关的症状的进展,稳定或改善,可以通过监测指示患者状况的病理生理变化来进行监测,基于该监测,确定患者的血管周围空间中是否存在淀粉样斑块,可以选择确定根据患者血管周间隙中淀粉样斑块的大小以及患者血管周间隙中淀粉样斑块的存在,确定患者的治疗方案。该治疗方案包括向患者施用源自将血液级分与脂质去除剂混合的高密度脂蛋白组合物。

著录项

  • 公开/公告号US2019381070A1

    专利类型

  • 公开/公告日2019-12-19

    原文格式PDF

  • 申请/专利权人 HDL THERAPEUTICS INC.;

    申请/专利号US201916409543

  • 发明设计人 HOLLIS BRYAN BREWER JR.;MICHAEL M. MATIN;

    申请日2019-05-10

  • 分类号A61K31/575;A61K35/16;A61K9;A61P25/28;A61B6/03;A61B5/055;A61M1/36;

  • 国家 US

  • 入库时间 2022-08-21 11:24:41

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