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HETEROCYCLIC INHIBITORS OF CBP/EP300 AND THEIR USE IN THE TREATMENT OF CANCER

机译:CBP / EP300的杂环抑制剂及其在癌症治疗中的用途

摘要

The present invention relates to compounds of formula (I) and formula (II): and to salts thereof, and compositions and uses thereof. The compounds are useful as inhibitors of CBP and/or EP300. Also included are pharmaceutical compositions comprising a compound of formula (I) of formula (II), or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various CBP and/or EP300-mediated disorders such as cancer, inflammatory disorders and autoimmune diseases.
机译:本发明涉及式(I)和式(II)的化合物:及其盐,及其组合物和用途。该化合物可用作CBP和/或EP300的抑制剂。还包括包含式(II)的式(I)化合物或其药学上可接受的盐的药物组合物,以及在治疗各种CBP和/或EP300介导的疾病例如癌症中使用此类化合物和盐的方法,炎症性疾病和自身免疫性疾病。

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