首页> 外国专利> METHOD FOR CONTROLLING PERIPHERAL NERVE, METHOD FOR DEVELOPING FUNCTION TO ALTER FUNCTION OF NERVE CELL IN ORGANS EXCLUDING BRAIN AND SPINAL CORD AND OTHERS, NOVEL METHOD FOR PREVENTING OR TREATING DISEASE, AND MEDICINE FOR APPLICATION TO PERIPHERAL NERVES

METHOD FOR CONTROLLING PERIPHERAL NERVE, METHOD FOR DEVELOPING FUNCTION TO ALTER FUNCTION OF NERVE CELL IN ORGANS EXCLUDING BRAIN AND SPINAL CORD AND OTHERS, NOVEL METHOD FOR PREVENTING OR TREATING DISEASE, AND MEDICINE FOR APPLICATION TO PERIPHERAL NERVES

机译:周围神经的控制方法,将脑和脊髓等器官除外的器官中的神经细胞的功能发展为功能的方法,预防或治疗疾病的新方法,以及应用于周围神经的药物

摘要

Provided is a method for preventing or treating a disease, said method being characterized in that a viral vector having, integrated thereinto, a gene encoding a protein having a function to kill, stimulate or depress peripheral nerves or a function to alter another nerve cell function is injected topically to an organ excluding brain and spinal cord, a tumor or an area that has undergone tumor resection to cause the infection of the nerves with the viral vector and consequently cause the expression of the protein having the above-mentioned function in the infected nerves, whereby the function of the nerves infected with the viral vector is controlled by the protein so that the function of the organ, excluding brain and spinal cord, to which the nerves are connected is altered. The method can be utilized for providing a therapeutic medicine and a treatment means in the medical industry. Particularly in cancer therapies, this method can be utilized widely both domestically and abroad in such a way that the viral vector is injected topically to a remaining cancer tissue postoperatively to suppress the recurrence or metastasis of the cancer.
机译:提供了一种预防或治疗疾病的方法,所述方法的特征在于病毒载体中整合有编码具有杀死,刺激或抑制周围神经功能或具有改变另一神经细胞功能的蛋白质的基因。将其局部注射到除脑和脊髓之外的器官,肿瘤或已切除肿瘤的区域中,以用病毒载体感染神经,并因此导致在感染者中表达具有上述功能的蛋白质神经,因此感染了病毒载体的神经的功能由蛋白质控制,从而改变了神经所连接的器官(大脑和脊髓除外)的功能。该方法可用于提供医学工业中的治疗药物和治疗手段。特别是在癌症疗法中,该方法可以在术后广泛地将病毒载体局部注射到剩余的癌组织中以抑制癌症的复发或转移,从而在国内外广泛使用。

著录项

  • 公开/公告号WO2018008770A1

    专利类型

  • 公开/公告日2018-01-11

    原文格式PDF

  • 申请/专利权人 NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER;

    申请/专利号WO2017JP25468

  • 发明设计人 KAMIYA ATSUNORI;

    申请日2017-07-05

  • 分类号A61K31/7088;A61K35/76;A61K48;A61P25/02;

  • 国家 WO

  • 入库时间 2022-08-21 12:46:27

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