COMPOSITIONS AND METHODS OF USING CHONDROITINASE ABCI MUTANTS

摘要

#$%^&*AU2016206267B220180705.pdf#####ABSTRACT The present invention relates to protein and nucleic acid mutants of chondroitinase ABCI. Such chondroitinase ABCI mutant enzymes exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided. See Figure 1.FIGURE 1 Enzyme Production Measured by Coomassie 60.0 50.0 j 40.0 30.0 0 0 1/3