Provided is a biological traditional Chinese medicine for oral administration for treating diabetes mellitus. The medicine for oral administration consists of a traditional Chinese medicine composition and an endogenous enzyme. The traditional Chinese medicine raw materials comprise: Bidens pilosa, Gynura divaricata, Potentilla chinensis, Agrimonia pilosa, American ginseng, Caulis Spatholobi, Cornus officinalis, Poria cocos, whole herb of Gynura divaricata, Uncaria rhynchophylla and Alpiniae oxyphyllae Fructus. The traditional Chinese medicine is prepared by means of a decoction method and an enzymolysis method. The enzymes used in the enzymolysis method are pectinase, lipase, amylase, soybean protease and cellulase. The endogenous enzyme comprises kallidinogenase, trypsin, DNA polymerase, dismutase, beer enzymes and papain.
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