METHODS TO CREATE A DOUBLE NANOEMULSION FOR TRANSDERMAL DELIVERY OF HYDROPHILIC AND HYDROPHOBIC PHYTOCHEMICAL ACTIVE INGREDIENTS.

摘要

#$%^&*AU2018101231A420180927.pdf#####ABSTRACT The present invention relates to topical compositions comprising plant extracts thereof in the form of double nanoemulsions. The composition comprises active ingredients which are either hydrophilic, hydrophobic or combinations thereof which are solubilised to nanoparticle size with at least one surface surfactant and one co-surfactant absorbed onto the surface of the nanoparticle. The invention provides a method of generating a double emulsion.