CYCLIC DINUCLEOTIDES CONTAINING BENZIMIDAZOLE, METHOD FOR THE PRODUCTION OF SAME, AND USE OF SAME TO ACTIVATE STIMULATOR OF INTERFERON GENES (STING)-DEPENDENT SIGNALING PATHWAYS

摘要

The invention relates to new cyclic dinucleotides which, unlike their natural representatives, carry lipophilic nucleobases and thus have higher membrane permeability and increased activity.