首页> 外国专利> FLUORESCENT GEL FOR GLUCOSE DETECTION AND CONTINUOUS GLUCOSE MONITORING METHOD USING SAME

FLUORESCENT GEL FOR GLUCOSE DETECTION AND CONTINUOUS GLUCOSE MONITORING METHOD USING SAME

机译:荧光胶用于葡萄糖检测和连续葡萄糖监测的相同方法

摘要

[Problem] To provide a novel fluorescent gel for glucose detection, in which gel fibrillation can be prevented even during prolonged implantation and which enables continuous glucose level measurement in vivo, and a continuous glucose monitoring using the fluorescent gel.[Solution] A fluorescent gel for glucose detection having a three-dimensional network structure in which a plurality of tetra-armed polymers having a polyethylene glycol skeleton are crosslinked together at the termini thereof, wherein a fluorochrome unit, said fluorochrome unit being capable of exhibiting a fluorescent response when bound to glucose, is immobilized in the gel structure via a covalent bond.
机译:[问题]提供一种用于葡萄糖检测的新型荧光凝胶,该荧光凝胶即使在长时间植入期间也可以防止凝胶原纤化,并可以在体内连续测量血糖水平,并使用该荧光凝胶进行连续葡萄糖监测。[解决方案]具有三维网络结构的葡萄糖检测用荧光凝胶,其中具有聚乙二醇骨架的多种四臂聚合物在其末端交联在一起,其中荧光染料单元,所述荧光染料单元能够显示出当与葡萄糖结合时,荧光反应通过共价键固定在凝胶结构中。

著录项

  • 公开/公告号WO2018135535A1

    专利类型

  • 公开/公告日2018-07-26

    原文格式PDF

  • 申请/专利权人 THE UNIVERSITY OF TOKYO;

    申请/专利号WO2018JP01239

  • 发明设计人 TAKEUCHI SHOJI;SAWAYAMA JUN;

    申请日2018-01-17

  • 分类号G01N21/78;G01N21/64;C09K11/06;

  • 国家 WO

  • 入库时间 2022-08-21 12:43:16

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