TREATMENT OF GLIAL CELL DERIVED NEUROTROPHIC FACTOR GDNF RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO GDNF

摘要

The present invention relates in particular to antisense oligonucleotides that modulate the expression and / or function of neurotrophic factor (GDNF) derived from glial germ cells by targeting natural antisense polynucleotides of neurotrophic factor (GDNF) derived from glial cells . The invention also relates to the identification of these antisense oligonucleotides and their use in the treatment of diseases and disorders associated with the expression of GDNF.