MSI- FSP MSI-SPECIFIC FRAMSHIFT PEPTIDES FSP FOR PREVENTION AND TREATMENT OF CANCER

摘要

The present invention provides a vaccine for the prevention and treatment of cancer characterized by microsatellite instability (MSI). The vaccine contains an MSI-specific framework shift peptide (FSP) that generates a humoral cellular response to cancer cells or a nucleic acid that encodes the FSP. In particular, the vaccine according to the present invention is useful for the prevention / treatment of colon cancer, endometrial cancer, stomach cancer or small intestine cancer.