- Method for screening autophagy modulator and method for diagnosing autophagy-related disease

摘要

The present invention relates to a method for screening an autophagy modulating agent, and a method for diagnosing autophagy-associated disease. More particularly, the present invention relates to a method for diagnosing an autophagy modulating agent or autophagy-associated disease by analyzing a degree of phosphorylation in at least one residue selected from the group consisting of the 391^st and 720^th serine in the LRS protein. According to the method of the present invention, it is possible to effectively screen the autophagy modulating agent, thereby being useful for the development of agents for preventing or treating autophagy-associated disease. In addition, it is also possible to provide information useful for diagnosing autophagy-associated disease.