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Chemokine activity, kinase activity and / or low molecular weight for cancer cell growth inhibition

机译:抑制癌细胞生长的趋化因子活性,激酶活性和/或低分子量

摘要

The present invention also relates to a method for the treatment and / or prophylaxis of diseases and disorders associated with the biological activity of a chemokine, such as inducing the death of cancer cells and / or regulating biological activity, such as cell migration, of the chemokine and / A compound capable of treating or using a disease or disorder associated with kinase inhibition and / or kinase activity, such as cancer and inflammatory diseases and disorders, is provided. The compounds are collectively represented by the formula (Ia) or (Ib) Wherein A, B, D, E, G and R 1 to R 5 are as defined herein.
机译:本发明还涉及一种用于治疗和/或预防与趋化因子的生物活性有关的疾病和病症的方法,所述疾病和紊乱例如诱导癌细胞的死亡和/或调节其的生物活性,例如细胞迁移。提供了趋化因子和/或化合物,其能够治疗或使用与激酶抑制和/或激酶活性有关的疾病或病症,例如癌症和炎性疾病和病症。这些化合物由式(Ia)或(Ib)共同表示,其中A,B,D,E,G和R 1 至R 5 如本文所定义。

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