The present invention relates to a protocol for inhibiting an immune rejection response which may occur upon corneal xenotransplantation. According to the immune response suppression method of the present invention, not only the immune rejection by the cornea transplanted after xenotransplantation can be effectively suppressed, but also the engraftment of the cornea can be maintained stably for a long period of time and corneal thickness and intraocular pressure can be effectively maintained, thereby being usefully used for xenotransplantation.
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