Clostridium tyrobutyricum with suppressed hydrogen production and use thereof

摘要

In the present specification, the antisense RNA molecule for suppressing hydrogenase gene expression, a composition comprising the same, a vector comprising a DNA sequence encoding the same, a DNA sequence encoding the antisense RNA molecule or a DNA sequence encoding the antisense RNA molecule, A host cell and a method for producing a substance using the host cell are disclosed. The use of this can inhibit the hydrogenation enzyme expression, thereby reducing hydrogen production, thereby increasing production of useful materials such as butyric acid, reducing by-products such as acetic acid, and effectively utilizing wood sugar to produce useful substances such as butyric acid have.