首页> 外国专利> G Novel polypeptide selective binding with mouse immunoglobulin G or rabbit immunoglobulin G and uses thereof

G Novel polypeptide selective binding with mouse immunoglobulin G or rabbit immunoglobulin G and uses thereof

机译:G与小鼠免疫球蛋白G或兔免疫球蛋白G的新型多肽选择性结合及其用途

摘要

The present invention relates to a novel polypeptide selectively binding to an immunoglobulin G of a mouse or a rabbit. More particularly, the present invention relates to a polypeptide binding to an immunoglobulin G of a mouse or rabbit, a polynucleotide encoding the polypeptide, A nucleotide-containing expression vector, a transformant into which the expression vector is introduced, a method for producing the polypeptide using the transformant, and a composition for immunoassay comprising the polypeptide. The novel polypeptide according to the present invention not only binds specifically to the immunoglobulin G of each mouse or rabbit and replaces the existing costly secondary immunoglobulin G and can be used in various biological immunoassays, It is useful for various immune sensor / immunization chip production and drug screening by using globulin G hybrid.
机译:本发明涉及选择性结合小鼠或兔子的免疫球蛋白G的新型多肽。更具体地,本发明涉及与小鼠或兔的免疫球蛋白G结合的多肽,编码该多肽的多核苷酸,含核苷酸的表达载体,导入该表达载体的转化体,该多肽的制备方法。使用转化体,以及用于免疫测定的包含该多肽的组合物。根据本发明的新型多肽不仅与每只小鼠或兔子的免疫球蛋白G特异性结合,并且替代了现有的昂贵的继发免疫球蛋白G,并且可以用于各种生物免疫测定中,对于各种免疫传感器/免疫芯片的生产和使用球蛋白G杂种进行药物筛选。

著录项

  • 公开/公告号KR101818152B1

    专利类型

  • 公开/公告日2018-02-28

    原文格式PDF

  • 申请/专利权人 한국과학기술원;

    申请/专利号KR20160012183

  • 申请日2016-02-01

  • 分类号C07K14/195;C12N15/62;C12N15/63;G01N33/533;G01N33/543;G01N33/544;

  • 国家 KR

  • 入库时间 2022-08-21 12:38:40

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