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VISIBLE LIGHT-CURABLE WATER-SOLUBLE CHITOSAN DERIVATIVE, CHITOSAN HYDROGEL, AND PREPARATION METHOD THEREFOR

机译:可见光固化的水溶性壳聚糖衍生物,壳聚糖水合物及其制备方法

摘要

The present invention relates to a visible light-curable water-soluble chitosan derivative, a hydrogel, and a preparation method therefor and, more specifically, to a visible light-curable glycol chitosan derivative which is cured by light in the visible light range and has wound healing ability, a hydrogel, and a preparation method therefor. A hydrogel obtained by cross-linkage of the visible light-curable glycol chitosan derivative according to the present invention using visible light has a wound healing effect per se, and further, a hydrogel obtained by cross-linkage in a combination of one or more growth factors has an excellent wound healing effect. In addition, the glycol chitosan hydrogel which can prevent the denaturation of contained drugs and growth factors due to the cross-linkage by visible light and is optimized for application to a wet dressing dosage form can be prepared.;COPYRIGHT KIPO 2018
机译:可见光可固化水溶性壳聚糖衍生物,水凝胶及其制备方法技术领域本发明涉及一种可见光可固化水溶性壳聚糖衍生物,其水凝胶及其制备方法,更具体地说,涉及一种通过可见光范围内的光固化的可见光可固化二醇壳聚糖衍生物。伤口愈合能力,水凝胶及其制备方法。通过使用可见光使根据本发明的可见光可固化的二醇壳聚糖衍生物交联而获得的水凝胶本身具有伤口愈合效果,并且,通过以一种或多种生长的组合交联而获得的水凝胶。因子具有优异的伤口愈合作用。此外,还可以制备乙二醇壳聚糖水凝胶,该凝胶壳聚糖水凝胶可防止由于可见光的交联而导致所含药物的变性和生长因子的变性,并针对湿敷料剂型进行了优化。; COPYRIGHT KIPO 2018

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