首页> 外国专利> VISIBLE LIGHT-CURABLE WATER-SOLUBLE CHITOSAN DERIVATIVE, CHITOSAN HYDROGEL, AND PREPARATION METHOD THEREFOR

VISIBLE LIGHT-CURABLE WATER-SOLUBLE CHITOSAN DERIVATIVE, CHITOSAN HYDROGEL, AND PREPARATION METHOD THEREFOR

机译:可见光固化的水溶性壳聚糖衍生物,壳聚糖水合物及其制备方法

摘要

A visible light-curable chitosan derivative, a hydrogel thereof, and a preparation method therefor are disclosed. The visible light-curable glycol chitosan derivative is curable by light in the visible light range and has a wound healing activity. A hydrogel obtained by cross-linkage of the visible light-curable glycol chitosan derivative using visible light has a wound healing effect per se, and further, a hydrogel obtained by cross-linkage in a combination of one or more growth factors has an excellent wound healing effect. In addition, a glycol chitosan hydrogel that can prevent the denaturation of contained drugs and growth factors due to the cross-linkage by visible light and is optimized for application to a wet dressing dosage form can be prepared.
机译:公开了一种可见光可固化的壳聚糖衍生物,其水凝胶及其制备方法。可见光可固化的二醇壳聚糖衍生物可被可见光范围内的光固化并具有伤口愈合活性。通过使用可见光将可见光可固化的二醇壳聚糖衍生物交联而获得的水凝胶本身具有伤口愈合效果,并且,通过将一种或多种生长因子组合交联而获得的水凝胶具有优异的伤口。愈合作用。另外,可以制备乙二醇壳聚糖水凝胶,其可以防止由于可见光的交联而导致所含药物和生长因子的变性,并且可以优化用于湿敷料剂型。

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